FROM THE PA TURNPIKE ( I-76): Get off at exit 17 and follow Route 15 North toward Harrisburg.  Follow this road which becomes Route 11/15 to the Camp Hill Bypass (AKA 21st St.)  Turn left onto 21st and continue on 21st which becomes Poplar Church Road for approx 2 miles.  Once you cross the intersection of Erford Road, look to your left for Yverdon Drive.  There is a sign which reads "Greek Orthodox Cathedral".  Turn left onto Yverdon Drive and go 4 blocks.  The Cathedral is on the left side.

Click on picture of Cathedral to see map
Picture of Holy Trinity Cathedral FROM I-81 SOUTH: Traveling from the North, follow I-81 South and get off at exit 21 (Enola/Marysville).  Follow Route 11/15 South to Enola.  Get off at Erford Road exit.  Turn right on Erford Road to Poplar Church Road.  Turn right on Poplar Church Road and follow directions above.
FROM I-83 NORTH: Traveling from the South, follow 83 North.  After Exit 19, look for sign for Camp Hill (Left Lane).  Follow exit ramp onto Route 581 for approx. 2 miles.  Get off at Route 11/15 North exit.  Follow Route 11/15 to Camp Hill Bypass (AKA 21st) and follow 1st directions above.